CannabisInteractions With Medical Marijuana And Other Medications

September 24, 2022by NHSOF MD

It typically doesn’t matter if it is a prescription drug or a recreational drug, all drugs have compounds that interact with other compounds, adverse interactions with cannabis appear rare. As example of drugs interaction there is caffeine, which most people take on a daily basis. Caffeine has over eighty known interactions with other substances. It is difficult to determine the relevance of a drug interaction, some of them are not harmful but given the number of variables it could change.


Before stopping your prescribed medications you must consult it with your healthcare provider. If you want professionals to tell you more about changing to a cannabis treatment avoiding dangerous interactions. People diagnosed with depression can be prescribed antidepressants, very little research has been made taking prescribed drugs while using cannabis. Side effects from antidepressants and other medications can be controlled with the use of medical and/or recreational marijuana use.

These sagacious medical marijuana cardholders have one stifling concern: Is it safe to use medical marijuana with prescribed prescribed drugs? For more on this topic you can also check the American Medical Association’s (AMA’s) research guide on how medical marijuana interacts with other medications.

However, there are other kind of risks to consider when mixing drugs and cannabis, antidepressants could be less effective or take longer to work, this could set the treatment on and off protocols, prolonging recovery. Patients with diabetes should be careful when their medication is set to lower blood sugar levels, as cannabis helps regulate blood sugar the effectiveness of the treatment could be compromised, we recommend measuring your blood sugar level while using metformin or a similar treatment and cannabis. Remember there are newer medications and research is needed, talk to your marijuana doctor if you want to consume cannabis while on medication.

The liver is key to drug interactions with cannabis. The liver uses enzymes, particularly one called CYP3A4, to metabolize and eliminate medical cannabis and other drugs from the body.  Aside from filtering out medical cannabis and other medications, the CYP enzymes are the primary culprits in causing drug interactions with cannabis. Additional Health Benefits.

The CYP enzymes don’t act the same with every prescription drug and medical cannabis. Some drugs interfere with the job being done by CYP3A4. This interference can block the metabolic processing of cannabis and other drugs. The interference in turn creates a backlog of drug concentrations waiting to be expelled from the body. Anytime the liver is holding an extra bag of drug concentrations, conditions are ripe for toxic side effects from prescription drug interactions with cannabis. Although these interactions can be negative, it is worth remembering that, in some instances, cannabis may help replace the need for more addictive and deadly pharmaceuticals. More Florida medical marijuana use information here.

If you are interested in meeting with a Florida medical marijuana doctor to discuss numerous option to treat your conditions with the use of marijuana, please reach out to NHSOF MD – medical marijuana doctors in Florida: who can assist you in getting a medical marijuana card to treat your medicinal alignments. Qualify for a Florida medical marijuana card certification at NHSOF MD today. We have locations all over the state of Florida to better assist you.